Explore AcceleDev’s white papers for practical insights into complex synthesis, purification, and process optimization challenges. Each paper features strategies developed by our Ph.D. chemists to accelerate early-phase development and improve scalability across the small-molecule lifecycle.
Unnatural amino acids are notoriously difficult to synthesize—but AcceleDev has built scalable, cost-effective strategies that outperform traditional approaches. This white paper showcases breakthrough case studies in Strecker synthesis, tyrosine derivative production, and phosphorylated UAA purification. A must-read for any team developing next-generation peptide therapeutics or seeking CDMOs capable of solving the hardest synthetic challenges.
Behind every successful drug program is a chemistry team that knows where to find efficiency. This paper reveals how AcceleDev’s senior chemists reduced step count, resolved scale-up issues, and delivered robust routes—faster and with fewer surprises. Packed with real-world examples, it’s designed for program managers and CMC leads who want to convert process R&D into measurable value.
At AcceleDev, biocatalysis isn’t just a trend. It’s a powerful, proven tool for achieving cleaner, more efficient, and scalable synthesis. This white paper focuses on enzyme-promoted transamination to create high-purity chiral amines and intermediates, sharing real-world case studies that demonstrate its advantages in yield, waste reduction, and sustainability. A practical, experience-driven guide for pharma teams evaluating when and how to use biocatalysis to move their programs forward.
AcceleDev combines green chemistry principles with real-world manufacturing expertise to deliver sustainable processes that actually scale. This paper highlights how solvent selection, route simplification, and waste reduction strategies are seamlessly embedded into early-phase development. Ideal for pharma teams who want to hit ESG goals without sacrificing project speed or success.
1. Advancing Innovation and Efficiency in Unnatural Amino Acid (UAA) Synthesis
2. Real-World ROI in Process R&D: How CDMO Chemistry Drives Drug Program Success
3. Biocatalysis as a Tool, Not a Buzzword: A CDMO’s Perspective
4. Green Chemistry in the Real World: Process Efficiency Meets Sustainability
