- Expert in process R&D of challenging, previously unproven, high value multi-step transformations
- Scale: Mg > G > Kg > MT
- Confidently accepting risks associated with lengthy 10-25 step new chemistry
- Proven track record, high success rate
- Facilities with well-equipped variety of unit operations
Process chemistry expertise
- Nitrations
- Brominations
- Alkylations
- Cross couplings
- Cyanurations
- Metal-catalyzed reactions
- Grignard/Lithium Reactions
- Biocatalysis
- Reductions/Oxidations
- Asymmetric reactions
- Moisture/air sensitive chemistry
- High/low temperature
- High pressure
- Hazardous Reactions
- Crystallization
- Continuous flow
Chemical structure expertise
- Natural or unnatural amino acids
- Heterocycles
- Carbohydrates
- Nucleosides
- Aromatics/Benzene derivatives
- Coupling agents (i.e. boronic acids)
- Chiral compounds with multiple stereocenters
- Chiral auxiliaries
- Chemical resolutions
- Dynamic Kinetic Resolutions
- Enzymatic resolutions